(Like many of my technology postings, this is really here for my own notes on problems I run into, the solutions I try and what works when. They are updated as I learn.)
I just can't seem to remember this so I need to post it.
Make the flyer/handbill as a full page in Word. File ==> Print. Under Print All Pages type "1,1,1,1". Last setting change to "4 page per sheet".